Violeta Guthrie

Lead Bioinformatics Scientist

United States
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Summary

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Senior
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Top School
Violeta Guthrie is a lead bioinformatics scientist with a decade of experience applying statistical modeling and machine learning to translational oncology, specializing in large-scale multi-omics integration and biomarker discovery. She has driven data-driven decisions across the cancer care continuum, from post-surgical prognostics to informing immuno-oncology trial stratification, and led multi-omics analyses for 20 IO trials at AstraZeneca. Violeta redesigned variant detection algorithms for multi-cancer early detection tests, improving early-stage sensitivity by over 20% and materially increasing expected life-years gained. She combines hands-on algorithm development with cross-functional leadership—aligning wet lab, software engineering, and clinical stakeholders—to translate complex molecular signals into actionable clinical insights. With a PhD from Johns Hopkins and a track record spanning startups, diagnostics, and pharma, she uniquely bridges deep computational rigor with pragmatic assay and clinical needs.
code10 years of coding experience
job2 years of employment as a software developer
bookJohns Hopkins University
bookMaster of Science - MS Physics Applied Mathematics, Master of Science - MS Physics Applied Mathematics at Kent State University
languagesGerman, Spanish, Russian, Bulgarian

Github contributions (1)

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KarchinLab/NAPA

Apr 2016 - Apr 2018

Contributions:37 commits, 7 pushes in 2 years
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Violeta Guthrie - Lead Bioinformatics Scientist