Will Holtz

Senior Staff Bioinformatics Data Scientist

Berkeley, California, United States
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Summary

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Senior
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Will Holtz is a Senior Staff Bioinformatics Data Scientist with 11 years of experience applying software engineering rigor to molecular biology problems, combining a Ph.D. in EECS from UC Berkeley with hands-on wet-lab and computational expertise. He has led cross-functional teams to productionize analysis pipelines, transition workflows to Nextflow/WDL, and overhaul CI/CD and security practices to deliver scalable, maintainable bioinformatics infrastructure. At Ansa he built ML classifiers that underpinned an on-time manufacturing guarantee and co-developed intelligent DNA assembly design software; earlier roles included founding scientific computing and wet-lab teams to automate DBTL cycles and implement LIMS and long-read genotype verification. Known for mentoring engineers from diverse backgrounds, he consistently reduces manual toil through automation and performance optimizations in metabolomics, genomics, and synthetic biology pipelines. Based in Berkeley, he blends electrical engineering discipline with biological intuition to solve practical problems at the interface of computation and wet-lab science. An under-the-radar strength is his track record of turning draft research workflows into production-grade, tested pipelines that cut hands-on time by more than half.
code11 years of coding experience
job12 years of employment as a software developer
bookPh.D. Electrical Engineering and Computer Science, Ph.D. Electrical Engineering and Computer Science at University of California, Berkeley
bookBS Electrical and Computer Engineering, BS Electrical and Computer Engineering at Carnegie Mellon University
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Stackoverflow

Stats
818reputation
33kreached
24answers
2questions
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Github Skills (200)

python10
openstack-swift10
dockerfile10
genomics10
cpp10
sftp10
encryption10
multiarch10
linux10
atlas10
ftp10
micromamba10
glibc10
mamba10
rapid10

Programming languages (19)

C#C++CSSCScalaGoHTMLPerl

Github contributions (5)

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mamba-org/micromamba-docker

Jan 2021 - Jan 2023

Rapid builds of small Conda-based containers using micromamba.
Contributions:2 releases, 8 reviews, 189 commits in 2 years
containersdockerfilecondabuildsdocker
biorack/metatlas

Jan 2021 - Jan 2023

Metabolite Atlas Main Repository
Contributions:3 releases, 764 commits, 910 PRs in 2 years
materials-informaticstsneatlas
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Will Holtz - Senior Staff Bioinformatics Data Scientist