Yang Li

Sr Scientist at Amgen

Thousand Oaks, California, United States
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Summary

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Senior
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Top School
Yang Li is a structural biologist and senior scientist with 8 years of experience applying NMR spectroscopy and X-ray crystallography to drug discovery and mechanistic biophysics. He has led fragment-based screening campaigns and structure-based antibody engineering, and now integrates ML to predict antibody biophysical properties at Amgen. His academic career includes impactful work on SHP2 and TCPTP inhibitors, rapid SARS-CoV-2 antibody screening by NMR, and elucidation of calcineurin regulation, reflecting a strong blend of structural, biophysical, and enzymology expertise. Trained as a Ph.D. in Structural Biology, he is also experienced in training and instrument stewardship across NMR, ITC, SPR and chromatography platforms—skills that often accelerate translational projects. Notably, he brings a proven ability to translate detailed mechanistic insight into practical screening and engineering workflows for both small molecules and biologics.
code8 years of coding experience
job10 years of employment as a software developer
bookDoctor of Philosophy (Ph.D.), Structural Biology, 3.8, Doctor of Philosophy (Ph.D.), Structural Biology, 3.8 at University of Wyoming
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Github Skills (5)

vms5
router5
merlin5
testing3
nas3

Programming languages (3)

RClassic ASPPython

Github contributions (5)

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leeyang1991/cui_project

Jun 2019 - Dec 2023

Contributions:73 pushes, 1 branch, 1 comment in 4 years 6 months
leeyang1991/lytools

Nov 2021 - Dec 2022

Contributions:85 commits, 111 pushes, 1 branch in 1 year 1 month
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Yang Li - Sr Scientist at Amgen