Summary
Yang Li is a structural biologist and senior scientist with 8 years of experience applying NMR spectroscopy and X-ray crystallography to drug discovery and mechanistic biophysics. He has led fragment-based screening campaigns and structure-based antibody engineering, and now integrates ML to predict antibody biophysical properties at Amgen. His academic career includes impactful work on SHP2 and TCPTP inhibitors, rapid SARS-CoV-2 antibody screening by NMR, and elucidation of calcineurin regulation, reflecting a strong blend of structural, biophysical, and enzymology expertise. Trained as a Ph.D. in Structural Biology, he is also experienced in training and instrument stewardship across NMR, ITC, SPR and chromatography platforms—skills that often accelerate translational projects. Notably, he brings a proven ability to translate detailed mechanistic insight into practical screening and engineering workflows for both small molecules and biologics.
8 years of coding experience
10 years of employment as a software developer
Doctor of Philosophy (Ph.D.), Structural Biology, 3.8, Doctor of Philosophy (Ph.D.), Structural Biology, 3.8 at University of Wyoming