Yang Li
Associate Professor
Greater Chicago Area United States
Summary
👤
Senior🎓
Top SchoolYang Li is an Associate Professor at the University of Chicago who leads a multidisciplinary lab of eight trainees and technicians studying the genetics and molecular mechanisms of RNA splicing in human disease. With a DPhil from Oxford and a decade of research experience spanning postdoctoral work at Stanford to independent faculty roles, Yang combines computational, genetic, and molecular approaches to translate splicing biology into potential therapeutic strategies. Their work emphasizes high-throughput sequencing and integrative genomics to pinpoint pathogenic splicing variation, and the lab explicitly aims to target splicing as a treatment modality. Based in Chicago, Yang bridges rigorous computational training (BSc in math and computer science) with hands-on experimental biology, enabling rapid iteration from prediction to validation. An accomplished mentor and lab leader, they are known for integrating quantitative methods into classical molecular biology to tackle complex disease mechanisms.
10 years of coding experience
6 years of employment as a software developer
DPhil, Clinical Medicine (Computational Biology), DPhil, Clinical Medicine (Computational Biology) at University of OxfordMPhil, Biological Sciences, MPhil, Biological Sciences at University of LiverpoolB.Sc., Math and Computer science, B.Sc., Math and Computer science at McGill University
English, French, Chinese
Github Skills (5)
rna-seq10
jack10
yang10
bioinformatics9
matlab3
Programming languages (3)
Github contributions (4)
davidaknowles/leafcutter
Dec 2015 - Apr 2020
Annotation-free quantification of RNA splicing. Yang I. Li, David A. Knowles, Jack Humphrey, Alvaro N. Barbeira, Scott P. Dickinson, Hae Kyung Im, Jonathan K. Pritchard
Contributions:20 commits, 3 PRs, 31 pushes in 4 years 4 months
splicingyangbioinformaticsrna-seqquantification
qhauck16/nmd_splicing_rules
Jul 2024 - Jul 2024
Contributions:1 push in 1 day
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