Yang Shen
Associate Professor
College Station, Texas, United States
Summary
👤
Senior🎓
Top SchoolYang Shen is an Associate Professor at Texas A&M with a decade of experience at the intersection of computational modeling, optimization, and molecular engineering. He develops algorithms for multimodal learning, protein complex structure prediction, and structure-based drug design, translating theoretical advances into practical tools for predicting genetic variant effects and engineering biological systems. His background includes postdoctoral work at MIT and research roles that produced faster global optimization methods for protein docking and insights into flexibility in molecular recognition relevant to HIV-1 inhibitor design. Known for blending rigorous algorithmic thinking with domain knowledge in systems and synthetic biology, he often leverages optimization and generative models to tackle hard biophysical problems. Based in College Station, Texas, he connects academic research with applied computational methods, and his career shows a steady trajectory from algorithm development in C++ to leading multidisciplinary projects. An underappreciated strength is his track record of turning complex physical chemistry questions into scalable computational solutions that inform experimental design.
10 years of coding experience
20 years of employment as a software developer
B.E Automatic Control, B.E Automatic Control at University of Science and Technology of ChinaPh.D Systems Engineering, Ph.D Systems Engineering at Boston University
Github Skills (10)
attention-mechanism10
affinity10
autoencoder10
semi-supervised-learning10
protein-sequences9
compound9
prediction9
drug-discovery8
deep-learning6
tensorflow5
Programming languages (1)
Github contributions (4)
Shen-Lab/DeepAffinity
May 2018 - Apr 2021
Protein-compound affinity prediction through unified RNN-CNN
Contributions:2 commits, 2 pushes in 2 years 11 months
autoencoderrnninterpretable-deep-learningpredictiondrug-discovery
Shen-Lab/cNMA
Sep 2016 - Nov 2016
Contributions:2 commits, 2 pushes in 1 month
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