Head Of Cell Therapy Advanced Technologies, Cell Therapy Discovery at AstraZeneca
Rockville, Maryland, United States
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Summary
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Senior
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Top School
Yasuhiro Ikeda is a strategic R&D leader with 25+ years advancing cell and gene therapies from concept to IND, currently heading Cell Therapy Advanced Technologies at AstraZeneca. He has driven development of eight CAR-T/CAR-Treg programs—including multiple first-in-human candidates—while building high-throughput CAR discovery platforms and viral vector engineering capabilities. Known for blending deep bench science (gene editing, iPSC differentiation, promoter engineering) with translational rigor, he has led teams up to 45 FTEs and shaped CMC and pre-IND strategy. He established hypoimmune universal cell programs and in vivo CAR delivery approaches, and pioneered COVID-pseudotyped lentivectors and HTP VHH/scFv CAR libraries that cut lead cycles by ~40%. A prolific scientist and mentor, he holds a PhD in Molecular Virology from the University of Tokyo with 150+ publications and multiple patents. Less obvious: he actively integrates AI-enabled tooling into discovery workflows to accelerate candidate design and due diligence.
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Yasuhiro Ikeda - Head Of Cell Therapy Advanced Technologies, Cell Therapy Discovery at AstraZeneca