Yi Zhang

Director, Pharmacometrics R&D at ICON plc

Seattle, Washington, United States
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Summary

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Rockstar
Yi Zhang is a Director of Pharmacometrics R&D based in Seattle with eight years of experience applying quantitative pharmacology and clinical data science to model-informed drug development. He blends Bayesian data analysis, optimal experimental design, and differential-equation modeling to translate complex clinical data into actionable development strategies. Comfortable with high-performance computing and software development, he leads efforts to build scalable tools that accelerate pharmacometric workflows. His work sits at the intersection of statistics, mechanistic modeling, and software engineering, enabling evidence-driven decisions across the drug lifecycle. Colleagues rely on him to turn mathematically rigorous approaches into practical solutions that improve trial design and dosing decisions. Outside core disciplines, he brings a pragmatic focus on production-ready implementations that bridge research and clinical application.
code8 years of coding experience
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Github Skills (83)

ode10
bayesian-data-analysis10
command-line-interface10
differentiation10
mcmc10
bayesian-methods10
cpp10
bayesian-inference10
simulate10
sampling10
eigen10
stan10
boost10
math-library10
r-package10

Programming languages (12)

TypeScriptRC++ShellCOCamlTeXStan

Github contributions (5)

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metrumresearchgroup/stanc3

Feb 2020 - Mar 2025

Rewriting the Stan compiler in OCaml
Contributions:12 releases, 75 pushes, 10 branches in 5 years 1 month
compilerstanrewritingocaml
metrumresearchgroup/cmdstan

Oct 2018 - Mar 2025

CmdStan, the command line interface to Stan
Contributions:124 pushes, 17 branches, 21 tags in 6 years 5 months
command-linecommand-line-interfacestancli
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Yi Zhang - Director, Pharmacometrics R&D at ICON plc