Yuanbin Ru

Associate Director, Translational Data Science

San Francisco Bay Area United States
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Summary

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Senior
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Top School
Yuanbin Ru is an Associate Director in Translational Data Science with over 15 years post-PhD experience applying bioinformatics, genomics, and machine learning to drug R&D across oncology, autoimmune, and genetic diseases. He has built data science functions from the ground up, led cross-functional biomarker and translational programs, and contributed to the discovery of 30+ drug candidates including multiple clinical-stage assets and approvals that generated $1.4B in 2024. A hands-on computational biologist, he develops and maintains widely used bioinformatics tools (e.g., multiMiR and CCM) and has combined open-source contributions—like force-layout improvements to d3—with deep translational expertise. Yuanbin routinely translates complex multi-omics signals into clinical-ready signatures and prognostic models, and he pairs that technical depth with a track record of mentoring teams and securing leadership alignment. Notably, his work spans both primary analysis of pivotal trials and development of reproducible pipelines for diverse assays, demonstrating rare end-to-end impact from algorithm to clinical submission.
code14 years of coding experience
job17 years of employment as a software developer
bookPh.D. Genetics, Ph.D. Genetics at Iowa State University
bookB.S. Plant Molecular and Developmental Biology, B.S. Plant Molecular and Developmental Biology at Peking University
languagesEnglish, Chinese, Chinese
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Github Skills (9)

javascript10
d3js10
visualizations9
data-visualisation9
data-visualization9
visualization9
data-visualizations9
svg8
charts7

Programming languages (15)

JavaC++CSSCRustPLpgSQLJupyter NotebookTypeScript

Github contributions (5)

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d3/d3

Sep 2011 - Sep 2011

Bring data to life with SVG, Canvas and HTML. :bar_chart::chart_with_upwards_trend::tada:
Role in this project:
userBack-end Developer
Contributions:11 commits in 1 day
Contributions summary:Yuanbin primarily worked on the `d3/d3` repository, focusing on the force layout functionality. They implemented features related to charge calculations for nodes, including node-dependent charges and adjustments to the accumulation process within the quadtree. Further contributions include modifying the charge method and updating internal calculations, demonstrating a clear focus on improving the force layout's core behavior.
chartschartsvgcanvasjavascript
yasirs/cmn

Jun 2011 - Aug 2011

Contributions:13 commits in 2 months
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Yuanbin Ru - Associate Director, Translational Data Science