Yunguan Wang
Assistant Professor at Cincinnati Children's Hospital Medical Center
Ohio, United States
Summary
👤
Senior🎓
Top SchoolYunguan Wang is an assistant professor and bioinformatics scientist with nine years of experience applying machine learning, multi-omics integration, and big-data mining to translational problems in drug discovery and spatial single-cell biology. He has built deep learning and latent-graph models for image and spatial transcriptomics denoising, designed large analysis pipelines that uncovered drivers in prostate cancer, translocation RCC, and SARS-CoV-2 immune responses, and led computational screens that prioritized small molecules for cystic fibrosis. His work bridges algorithm development and wet-lab validation—screening over a million L1000 profiles to nominate compounds that restored CFTR function—demonstrating an uncommon end-to-end competence from model to experiment. Based in Ohio, he combines PhD-level bioinformatics training with practical data science roles at leading institutions (Harvard, UT Southwestern, Cincinnati Children’s), consistently translating high-dimensional data into testable biological hypotheses.
9 years of coding experience
9 years of employment as a software developer
Doctor of Philosophy - PhD, Bioinformatics, Doctor of Philosophy - PhD, Bioinformatics at University of Cincinnati College of MedicineB.E., Bioengineering, B.E., Bioengineering at Dalian University of Technology
English, Chinese
Stackoverflow
23reputation
710reached
0answers
1question
Github Skills (53)
spatial-transcriptomics10
structural-variation10
single-cell-analysis10
single-cell-genomics9
reproducible-research9
profiling9
transcriptomics9
medicine9
spatial9
computational-biology8
ide7
electrophysiology7
differential-expression7
quantitative7
go6
Programming languages (10)
Github contributions (5)
yunguan-wang/SPROD
Mar 2021 - Dec 2022
SPROD: Spatial expression profiling de-noising
Contributions:1 release, 178 commits, 21 PRs in 1 year 9 months
single-cell-genomicsprofilingspatial-transcriptomicsstructural-variationrnaseq
yunguan-wang/Spacia
Sep 2023 - Mar 2025
Contributions:29 PRs, 67 pushes, 2 branches in 1 year 5 months
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