Zack Manning is a Founding Principal Engineer in Portland with 13 years of experience building and leading teams that deliver large-scale distributed systems and ML-driven production services. He combines hands-on systems engineering—optimizing real-time inference, GPU sharing, and cost-efficient concurrency—with proven management of engineering organizations at companies from startups to Amazon and Vevo. His work spans building secure, compliant ML infrastructure (SOC2/HIPAA), driving measurable product lift in personalization systems, and establishing operational excellence and hiring practices. Comfortable toggling between deep technical contributions and strategic leadership, he’s recently focused on applying AI to clinical trial research and accessibility, bringing a rare mix of production ML ops, systems performance tuning, and organizational ownership.
13 years of coding experience
16 years of employment as a software developer
BS Information Systems, BS Information Systems at Portland State University
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Zack Manning - Founding Principal Engineer at HumanTrue