Assistant Professor at Thomas Jefferson University
Athens-Clarke County Unified Government, Georgia, United States
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Summary
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Zheng Ruan is an Assistant Professor and computational biologist with 13 years of experience bridging bioinformatics research and software development. He earned a Ph.D. in Bioinformatics from the University of Georgia, completed a postdoc at Van Andel Institute, and now leads research and teaching at Thomas Jefferson University. Zheng has deep expertise in codon-aware sequence analysis and evolutionary genomics, exemplified by his contributions to Biopython’s codonalign module, dN/dS estimation, and McDonald–Kreitman test implementations. Comfortable moving between academia and open-source engineering, he combines rigorous methodological development with production-ready code for widely used bioinformatics tools. Colleagues value his ability to translate complex evolutionary questions into efficient algorithms and reusable software.
12 years of coding experience
9 years of employment as a software developer
University of Georgia
Bachelor’s Degree Biotechnology, Bachelor’s Degree Biotechnology at Huazhong Agricultural University
Official git repository for Biopython (originally converted from CVS)
Role in this project:
Back-end Developer
Contributions:1 review, 106 commits, 9 PRs in 7 years 4 months
Contributions summary:Zheng implemented core features and improvements for the Biopython library, specifically focused on codon alignment functionality. They developed a new CodonAlignment class, incorporating codon-aware slicing and translation capabilities. Furthermore, the user added dN/dS ratio estimation and McDonald-Kreitman test support, indicating work on evolutionary analysis tools. Several commits demonstrate the user's contributions to adding support for multiple frameshift, and more sophisticated sequence comparison algorithms.
Official git repository for Biopython (converted from CVS)
Contributions:2 PRs, 33 pushes, 3 branches in 5 years
git-repositorypythonconvertedbiopythoncvs
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Zheng Ruan - Assistant Professor at Thomas Jefferson University